Osteosclerotic myeloma with polyneuropathy and hypocalcemia
✍ Scribed by Ludescher, Christof ;Gr�newald, Kurt ;Fend, Falko ;Dietze, Otto ;Thaler, Josef ;Schmid, Kurt Werner
- Publisher
- Springer-Verlag
- Year
- 1989
- Weight
- 758 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1432-0584
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We describe a patient with a 3 year history of progressive polyneuropathy that rendered him severely quadriparetic and bedridden. Work up revealed an IgG lambda monoclonal spike and multifocal osteosclerotic myeloma. Remarkable improvement followed combined treatment with surgical excision, radiatio
Metabolic bone disease is a major cause of morbidity and mortality in patients suffering from multiple myeloma. This usually results from an imbalance between the osteoclast and osteoblast activity of bone resorption and formation due to the secretion of an osteoclast-activating factor by the myelom
Multiple myeloma usually is characterized by the development of lytic bone lesions. Osteosclerotic myeloma is a rare entity characterized by a single or multiple osteosclerotic bone lesions and often accompanied by a demyelinating polyneuropathy. Multiple myeloma associated with widespread osteoscle