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Polymorphs and solvates of felodipine: analysis of crystal structures and thermodynamic aspects of sublimation and solubility processes

โœ Scribed by Perlovich, German L.; Blokhina, Svetlana V.; Manin, Nikolay G.; Volkova, Tatyana V.; Tkachev, Valery V.

Book ID
119969946
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
969 KB
Volume
14
Category
Article
ISSN
1466-8033

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Polymorph screening of formoterol fumarate was performed in 12 solvents, followed by evaluations of thermodynamic stability. Three anhydrates, a dihydrate, a diethanolate, a diisopropanolate, and a dibensylalcoholate were found. The crystal structure of three solvated modifications and of the most s