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Polymorphisms of dopamine receptor and transporter genes and hallucinations in Parkinson's disease

✍ Scribed by Jian Wang; Chunying Zhao; Biao Chen; Zhuo-Lin Liu

Book ID: 116766245
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 78 KB
Volume: 355
Category: Article
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2003.11.006

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.