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Polymorphisms inFZD3andFZD6genes and risk of neural tube defects in a northern Han Chinese population

✍ Scribed by Shi, Ou-Yan; Yang, Hui-Yun; Shen, Yong-Ming; Sun, Wei; Cai, Chun-You; Cai, Chun-Quan

Book ID
125351987
Publisher
Springer Milan
Year
2014
Tongue
English
Weight
502 KB
Volume
35
Category
Article
ISSN
1590-1874

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Thymidylate synthase repeat polymorphism
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## Abstract ## BACKGROUND A 28‐bp repeat polymorphism in the 5β€²UTR of the thymidylate synthase (__TYMS__) gene represents a candidate risk factor for neural tube defects (NTDs) due to involvement in folate‐dependent homocysteine metabolism. Non‐Hispanic, white, U.S. citizens carrying at least one