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Maternal PCMT1 gene polymorphisms and the risk of neural tube defects in a Chinese population of Lvliang high-risk area

✍ Scribed by Huizhi Zhao; Fang Wang; Jianhua Wang; Hua Xie; Jin Guo; Chi Liu; Li Wang; Xiaolin Lu; Yihua Bao; Guoliang Wang; Rugang Zhong; Bo Niu; Ting Zhang


Book ID
116508941
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
500 KB
Volume
505
Category
Article
ISSN
0378-1119

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## Abstract ## BACKGROUND A 28‐bp repeat polymorphism in the 5β€²UTR of the thymidylate synthase (__TYMS__) gene represents a candidate risk factor for neural tube defects (NTDs) due to involvement in folate‐dependent homocysteine metabolism. Non‐Hispanic, white, U.S. citizens carrying at least one