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Polymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosy

✍ Scribed by P.-Y. Bochud; D. Sinsimer; A. Aderem; M. R. Siddiqui; P. Saunderson; S. Britton; I. Abraham; A. Tadesse Argaw; M. Janer; T. R. Hawn; G. Kaplan


Book ID
106272157
Publisher
Springer
Year
2009
Tongue
English
Weight
259 KB
Volume
28
Category
Article
ISSN
0934-9723

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Innate immune signaling by Toll-like rec
✍ Masayuki Fukata; Yasmin Hernandez; Daisy Conduah; Jason Cohen; Anli Chen; Keith πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 831 KB

## Background: Patients with ulcerative colitis are at increased risk for developing colorectal cancer. we have shown that toll-like receptor-4 (tlr4) is overexpressed in human colitis-associated cancer (cac) and that mice deficient in tlr4 are markedly protected against colitis-associated neoplasi