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Polymorphisms in the promoter region of the tumor necrosis alpha (TNF-) gene in women with cervical insufficiency

✍ Scribed by Jennifer Warren; Robert Silver; Jess Dalton; Lesa Nelson; Kristi Nelson; Flint Porter; Ware Branch


Book ID
113431783
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
56 KB
Volume
195
Category
Article
ISSN
1097-6868

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The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor ␣ (TNF ␣) is located in the HLA class II gene cluster. Recent studies