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Polymorphism in the promoter region of tumor necrosis factor-alpha gene is associated with severe melioidosis

โœ Scribed by Sirithip Nuntayanuwat; Tararaj Dharakul; Wipada Chaowagul; Sirirurg Songsivilai

Book ID
117415910
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
235 KB
Volume
60
Category
Article
ISSN
0198-8859

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Novel polymorphism in the promoter region of the tumor necrosis factor alpha gene: No association with narcolepsy
โœ Kato, Tadafumi; Honda, Makoto; Kuwata, Shouji; Juji, Takeo; Kunugi, Hiroshi; Nan ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 22 KB ๐Ÿ‘ 3 views

The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor โฃ (TNF โฃ) is located in the HLA class II gene cluster. Recent studies