## Abstract ## BACKGROUND. In estrogen biosynthetic pathways, many enzymes are important for metabolism, detoxification, and bioavailability. Polymorphisms in these genes may have an effect on the enzymes' function. For example, higher expression and activation of biosynthetic enzymes and lower ex
Polymorphisms in sulfotransferases SULT1A1 and SULT1A2 are not related to colorectal cancer
β Scribed by Victor Moreno; Hansruedi Glatt; Elisabet Guino; Eva Fisher; Walter Meinl; Matilde Navarro; Josep M. Badosa; Heiner Boeing; Bellvitge Colorectal Cancer Study Group
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- French
- Weight
- 63 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0020-7136
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## Abstract Sulfotransferase (SULT) 1A1 detoxifies and bioactivates a broad spectrum of substrates including xenobiotics. It has been suggested that the __SULT1A1 his__ (__histidine__) allele, which is caused by a __his__ for __arg__ (__arginine__) substitution due to a GβA transition at codon 213,
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