𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma

✍ Scribed by Carmen S. P. Lima; Helvia Nascimento; Luciana C. Bonadia; Maria T. Teori; Claudio S. R. Coy; Juvenal R. N. Góes; Fernando F. Costa; Carmen S. Bertuzzo

Publisher
Springer
Year
2006
Tongue
English
Weight
171 KB
Volume
22
Category
Article
ISSN
0179-1958

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Association between methylenetetrahydrof
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
✍ Maria Vares; Peter Saetre; Hong Deng; Guiqing Cai; Xiehe Liu; Thomas Hansen; Hen 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 2 views

## Abstract Different lines of evidence indicate that methylenetetrahydrofolate reductase (__MTHFR__) functional gene polymorphisms, causative in aberrant folate–homocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are exp

Methylenetetrahydrofolate reductase (MTH
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: A combined analysis of independent samples
✍ Peter Saetre; Maria Vares; Thomas Werge; Ole A. Andreassen; Tadao Arinami; Hirok 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 1 views

Methylenetetrahydrofolate reductase (MTHFR) is involved in the one-carbon cycle, which is of importance for nucleotide synthesis and methylation of DNA, membranes, proteins and lipids. The MTHFR gene includes two common polymorphisms (rs1801133 or C677T; rs1801131 or A1298C) which both alter enzyme

Distribution of alleles of the methylene
Distribution of alleles of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in familial spina bifida
✍ Johnson, William G.; Stenroos, Edward S.; Heath, Simon C.; Chen, Yanping; Carrol 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 28 KB 👁 2 views

Spina bifida cystica (SB) is one of the most common and disabling of birth defects. Folic acid supplementation in mothers during the periconceptional period has been shown to prevent more than 70% of neural tube defects (NTD) including SB. However, the mechanism is unknown. We tested a series of mul

Characterization of six novel mutations
Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria
✍ Sahar Sibani; Benedicte Christensen; Erin O'Ferrall; Irfan Saadi; François Hiou- 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB 👁 2 views

## Communicated by Mark Paalman Severe deficiency of methylenetetrahydrofolate reductase (MTHFR) is the most common inborn error of folate metabolism. Patients are characterized by severe hyperhomocysteinemia, homocystinuria and a variety of neurological and vascular problems. Eighteen rare mutatio