## Abstract The aims of this study were to analyze flavinβcontaining monooxygenase __3 (FMO3)__ polymorphisms and allele and genotype frequencies in 256 Han Chinese and 50 AfricanβAmerican individuals, to compare the allele and genotype frequencies of these populations with those of other world pop
Genotype and allele frequencies of the polymorphic methylenetetrahydrofolate reductase gene in Turkey
β Scribed by Dr Ali Sazci; Emel Ergul; Guner Kaya; Ihsan Kara
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 57 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1132
No coin nor oath required. For personal study only.
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Spina bifida cystica (SB) is one of the most common and disabling of birth defects. Folic acid supplementation in mothers during the periconceptional period has been shown to prevent more than 70% of neural tube defects (NTD) including SB. However, the mechanism is unknown. We tested a series of mul
## Abstract Hyperhomocysteinemia is a risk factor for thrombosis, and methylenetetrahydrofolate reductase (__MTHFR__) and methionine synthase reductase (__MTRR__) polymorphisms, folate, and B~12~ levels could contribute to plasma homocysteine (Hcy) variation. Although well established in adults, fe
## Abstract ## BACKGROUND Folate deficiency is a known factor contributing to the formation of neural tube defects (NTDs). Many folate metabolism gene variants have been investigated, but only a few substantial associations have been established, the C677T polymorphism of the __methylenetetrahydro