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Polymorphisms in manganese superoxide dismutase, myeloperoxidase and glutathione-S-transferase and survival after treatment for metastatic breast cancer

✍ Scribed by Mary A. Bewick; Michael S. C. Conlon; Robert M. Lafrenie


Publisher
Springer US
Year
2007
Tongue
English
Weight
245 KB
Volume
111
Category
Article
ISSN
0167-6806

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## Abstract Glutathione __S__‐transferase (GST) enzymes detoxify chemotherapeutic drugs, and several studies have reported differences in survival for cancer patients who have variant genotypes for GSTP1, GSTM1 or GSTT1 enzymes. A recently described polymorphism alters hepatic expression of GSTA1,