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Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome in China

โœ Scribed by Shao-shuai Wang; Fu-yuan Qiao; Ling Feng; Juan-juan Lv

Book ID
111842199
Publisher
SP Zhejiang University Press
Year
2008
Tongue
English
Weight
249 KB
Volume
9
Category
Article
ISSN
1673-1581

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## Abstract Associations between specific alleles of genes encoding enzymes in the methionine/homocysteine pathway and plasma homocysteine levels have been examined in different populations. In the present study, we determined polymorphisms of __MTHFR__ A222V (677Cโ€‰>โ€‰T), __MTHFR__ E429A (1298Aโ€‰>โ€‰C)