𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Maternal gene polymorphisms involved in folate metabolism and risk of Down syndrome offspring: a meta-analysis

✍ Scribed by Elias Zintzaras

Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
281 KB
Volume
52
Category
Article
ISSN
1435-232X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Relationship between polymorphisms in ge
Relationship between polymorphisms in genes involved in homocysteine metabolism and maternal risk for Down syndrome in Brazil
✍ Luciana Rodrigues Jacy da Silva; Naja Vergani; Luciano de Camargo Galdieri; Mari πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 76 KB πŸ‘ 2 views

## Abstract Associations between specific alleles of genes encoding enzymes in the methionine/homocysteine pathway and plasma homocysteine levels have been examined in different populations. In the present study, we determined polymorphisms of __MTHFR__ A222V (677C > T), __MTHFR__ E429A (1298A > C)

Abnormal folate metabolism and genetic p
Abnormal folate metabolism and genetic polymorphism of the folate pathway in a child with Down syndrome and neural tube defect
✍ Al-Gazali, L.I. ;Padmanabhan, R. ;Melnyk, S. ;Yi, P. ;Pogribny, I.P. ;Pogribna, πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 86 KB πŸ‘ 2 views

The association of neural tube defects (NTDs) with Down syndrome (trisomy 21) and altered folate metabolism in both mother and affected offspring provide a unique opportunity for insight into the etiologic role of folate deficiency in these congenital anomalies. We describe here the case of a male c