## Abstract We evaluated the influence of several DNA repair gene polymorphisms on the frequency of chromosomal aberrations (CAs) analyzed in peripheral lymphocytes, using the fluorescence in situ hybridization technique. The CA data were obtained from an earlier study of 84 healthy nonsmokers (48
Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer
โ Scribed by Carsten Harms; Salama A. Salama; Carlos H. Sierra-Torres; Nohelia Cajas-Salazar; William W. Au
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 98 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20031
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## Abstract ## BACKGROUND: Several reports have revealed the association between single nucleotide polymorphisms (SNPs) and the development of cancer. Although many SNPs have been investigated, they were tested individually. In this study, nonsynonymous SNPs present in DNA damage response genes we