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Polymorphisms and haplotypes in the human immunoglobulin x locus

✍ Scribed by Walter Pargent; Karlheinz F. Schäble; Hans G. Zachau

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
630 KB
Volume
21
Category
Article
ISSN
0014-2980

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The proximal promoter region of the human pituitary expressed growth hormone (GH1) gene is highly polymorphic, containing at least 15 single nucleotide polymorphisms (SNPs). This variation is manifest in 40 different haplotypes, the high diversity being explicable in terms of gene conversion, recurr