Polymorphism of α1-antitrypsin in a Portuguese population
✍ Scribed by Helena Manuela Geada; J. A. Pereira Albino; Carlos Manso
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 244 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
Serum Pi phenotypes were studied in 219 samples. The MM phenotype was the most common as in all other populations. The frequencies of PiS and PiZ were high considering other populations. PiF was not detected.
📜 SIMILAR VOLUMES
alpha1-Antitrypsin types were determined in 200 individual specimens of Malaysian Macaca irus. We found the pattern B in 76 samples, BC in 116, and C in 8. Assuming that these patterns are determined by codominant alleles at one locus, this distribution constitutes a significant (P less than 0.001)
Two groups of 708 healthy blood donors and 563 patients affected with chronic obstructive lung disease (C.O.L.D.) respectively, have been screened for al-antitrypsin (alAT) variants by electrophoresis on agarose-polyacrylamide gels at pH 4.7 and isoelectric focusing (IEF). The frequencies of the Pi