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Polymorphism of the thymidylate synthase gene and outcome of acute lymphoblastic leukaemia

✍ Scribed by M Krajinovic; I Costea; S Chiasson

Book ID
117280193
Publisher
The Lancet
Year
2002
Tongue
English
Weight
58 KB
Volume
359
Category
Article
ISSN
0140-6736

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## Abstract Xenobiotic and folate metabolic pathways are important for the maintenance of genetic stability and may influence susceptibility to the development of childhood acute lymphoblastic leukaemia (ALL). In this study, we investigated 10 polymorphisms in 6 genes (__GSTM1__‐present/null, __GST