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Polymorphism of the promoter region of prostacyclin synthase gene is not related to essential hypertension

✍ Scribed by Tomohiro Nakayama; Masayoshi Soma; Yukie Takahashi; Duolikun Rehemudula; Hideko Tobe; Mikano Sato; Jiro Uwabo; Masako Kunimoto; Yoichi Izumi; Katsuo Kanmatsuse

Book ID
117599709
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
59 KB
Volume
14
Category
Article
ISSN
0895-7061

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Functional polymorphism of the promoter
Functional polymorphism of the promoter region of the prostacyclin synthase gene and severity of RSV infection in hospitalized children
✍ Koichi Hashimoto; Kei Ishibashi; Tebeb Gebretsadik; Tina V. Hartert; Akihiro Yam πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 120 KB

Prostaglandin I 2 (PGI 2 ) protects against RSVinduced illness in mice. A variable-number tandem repeat (VNTR) polymorphism has been detected in the promoter region of the PGI 2 synthase (PGIS) gene. We sought to determine if PGI 2 concentrations or polymorphisms of the PGIS gene correlate with seve