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Polymorphism of the promoter region of prostacyclin synthase gene in chronic thromboembolic pulmonary hypertension

✍ Scribed by Shinya AMANO; Koichiro TATSUMI; Nobuhiro TANABE; Yasunori KASAHARA; Katsushi KUROSU; Yuichi TAKIGUCHI; Yoshitoshi KASUYA; Sadao KIMURA; Takayuki KURIYAMA

Book ID
108964188
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
127 KB
Volume
9
Category
Article
ISSN
1323-7799

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Prostaglandin I 2 (PGI 2 ) protects against RSVinduced illness in mice. A variable-number tandem repeat (VNTR) polymorphism has been detected in the promoter region of the PGI 2 synthase (PGIS) gene. We sought to determine if PGI 2 concentrations or polymorphisms of the PGIS gene correlate with seve