Polymorphism of esterase 11 inMus musculus, a further esterase locus on chromosome 8
β Scribed by Josephine Peters; H. R. Nash
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 561 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0006-2928
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β¦ Synopsis
A further esterase, esterase 11, which exhibits a polymorphism detectable by electrophoresis, has been observed in the house mouse, Mus musculus. In 15 inbred strains and two outbred strains, the ES-11A phenotype has been found, composed of two bands of enzyme activity of greater anodal electrophoretic mobility than the two bands of the ES-11B phenotype found in one inbred strain, one wild stock, and 101 wild mice. In F1 hybrids (IS/Cam X C57BL/Gr), the phenotype shown corresponds to a mixture of the two parental phenotypes. In backcrosses, ES-11 segregates as an autosomal gene, designated Es-11, closely linked to Es-2 and Es-5 on chromosome 8.
π SIMILAR VOLUMES
A polymorphismfor an isozyme of a presumed arylesterase, esterase-16 (EC 3.1.1.2), has been detected in kidney, heart, and spleen of the house mouse, Mus musculus, by means of isoelectric focusing and by disc electrophoresis. Three phenotypes can be distinguished." the ES-16A phenotype (IEP 5.9) was