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Polymorphism of alanine aminotransferase (E.C.2.7.6.1): Common and rare alleles

✍ Scribed by J. Kömpf; H. Ritter

Publisher
Springer
Year
1979
Tongue
English
Weight
668 KB
Volume
51
Category
Article
ISSN
0340-6717

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✦ Synopsis

Gene frequencies of common and rare GPT alleles derived from an investigation of 1139 unrelated, healthy individuals from southwestern Germany are given. GPT typing was performed by means of horizontal starch gel electrophoresis in a Tris-histidine x HCl buffer system. In addition, a new electrophoretic variant, GPT9, is described. The frequencies of the GPT alleles observed were calculated as: GPT1, 0.4987; GPT2, 0.4686; GPT1M, 0.022; GPT0, 0.005; GPT3, 0.0022; GPT4, 0.0025; GPT8, 0.0005; GPT9, 0.0005.

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