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Polymorphism at 3′ UTR +28 of the prion-like protein gene is associated with sporadic Creutzfeldt–Jakob disease

✍ Scribed by Jeong, Byung-Hoon; Kim, Nam-Ho; Choi, Eun-Kyoung; Lee, Chaeyoung; Song, Young-Han; Kim, Jae-Il; Carp, Richard I; Arnold, Peter S


Book ID
110026364
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
84 KB
Volume
13
Category
Article
ISSN
1018-4813

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Polymorphisms of the prion protein gene
✍ Mirella Salvatore; Maurizio Genuardi; Rosella Petraroli; Carlo Masullo; Marco D' 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 593 KB

Creutzfeldt-Jakob disease (CJD) is a transmissible neurodegenerative disorder characterized by the accumulation of the amyloid protein PrP in the CNS. Two coding polymorphisms of the PrP gene (PRNP) are a methionine (Met) to valine (Val) change at codon 129, and a deletion in the octapeptide coding