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Polymorphic DNA haplotypes and ΔF508 deletion in 212 Italian CF families

✍ Scribed by Giuseppe Novelli; Paolo Gasparini; Anna Savoia; Pier Franco Pignatti; Federica Sangiuolo; Bruno Dallapiccola


Publisher
Springer
Year
1990
Tongue
English
Weight
214 KB
Volume
85
Category
Article
ISSN
0340-6717

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Deletion ΔF508 and haplotype analysis of
✍ L. Kádasi; J. Gécz; J. Matúšek; T. Krivušová; V. Ferák; M. Devoto; J. Hruškovič; 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 205 KB

Analysis of a sample of 50 unrelated cystic fibrosis (CF) patients and 46 nuclear families from Slovakia (Czechoslovakia) by the polymerase chain reaction and Southern hybridization revealed that the proportion of the delta F508 mutation was 58% in this population, and that the frequency of the B (i