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The incidence of ΔF508 CF mutation, and associated haplotypes, in a sample of English CF families

✍ Scribed by Eila K. Watson; Edward S. Mayall; Lidija Simova; Elizabeth M. Thompson; John O. Warner; Robert Williamson; Carolyn Williams


Publisher
Springer
Year
1990
Tongue
English
Weight
245 KB
Volume
85
Category
Article
ISSN
0340-6717

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Analysis of a sample of 50 unrelated cystic fibrosis (CF) patients and 46 nuclear families from Slovakia (Czechoslovakia) by the polymerase chain reaction and Southern hybridization revealed that the proportion of the delta F508 mutation was 58% in this population, and that the frequency of the B (i