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Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters

✍ Scribed by Ferguson, Ronald J.; Doll, Mark A.; Baumstark, Barbara R.; Hein, David W.


Book ID
123440002
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
297 KB
Volume
140
Category
Article
ISSN
0378-1119

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## Abstract __N__‐acetyltransferase 1 (NAT1) and 2 (NAT2) enzymes catalyzing both deactivation (__N__‐acetylation) and activation (__O__‐acetylation) of arylamine carcinogens such as 4‐aminobiphenyl (ABP) were investigated in a Syrian hamster model congenic at the __NAT__2 locus. NAT2 catalytic act