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Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters

✍ Scribed by Ferguson, Ronald J.; Doll, Mark A.; Baumstark, Barbara R.; Hein, David W.

Book ID: 123440002
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 297 KB
Volume: 140
Category: Article
ISSN: 0378-1119
DOI: 10.1016/0378-1119(94)90552-5

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## Abstract __N__‐acetyltransferase 1 (NAT1) and 2 (NAT2) enzymes catalyzing both deactivation (__N__‐acetylation) and activation (__O__‐acetylation) of arylamine carcinogens such as 4‐aminobiphenyl (ABP) were investigated in a Syrian hamster model congenic at the __NAT__2 locus. NAT2 catalytic act