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Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(ε-caprolactone) copolymer as a carrier for paclitaxel

✍ Scribed by Sang Cheon Lee; Chulhee Kim; Ick Chan Kwon; Hesson Chung; Seo Young Jeong


Book ID
114162358
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
342 KB
Volume
89
Category
Article
ISSN
0168-3659

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✍ Stefan G. Krimmer; Huaizhong Pan; Jihua Liu; Jiyuan Yang; Jindřich Kopeček 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 747 KB

## Abstract Amphiphilic block copolymers based on HPMA and ε‐CL were synthesized by ring‐opening polymerization of ε‐CL followed by RAFT polymerization of HPMA. A copolymer composed of 34 kDa PHPMA and 8.5 kDa PCL associated into micelles with CMC of 5.4 µg · mL^−1^. A novel retinoid, 3‐Cl‐AHPC‐OMe