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Polymeric 6-aminoquinoline, an activated carbamate reagent for derivatization of amines and amino acids by high-performance liquid chromatography

✍ Scribed by J.H. Yu; G.D. Li; I.S. Krull; S. Cohen


Publisher
Elsevier Science
Year
1994
Weight
913 KB
Volume
658
Category
Article
ISSN
0378-4347

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A highly reactive amine derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, has been synthesized. In a rapid, one-step procedure, the compound reacts with amino acids to form stable unsymmetric urea derivatives which are readily amenable to analysis by reversed phase HPLC. Studies