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Polymerase Recognition of Unnatural Base Pairs

✍ Scribed by Chengzhi Yu; Allison A. Henry; Floyd E. Romesberg; Peter G. Schultz

Book ID
101559902
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
22 KB
Volume
41
Category
Article
ISSN
0044-8249

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The storage and replication of genetic information requires bases that pair stably and selectively in duplex DNA and are also good substrates for DNA polymerases. Though the four natural bases pair by hydrogen bonding, there is no reason to assume that the pairing of two unnatural bases could not be

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