Major Groove Substituents and Polymerase Recognition of a Class of Predominantly Hydrophobic Unnatural Base Pairs
✍ Scribed by Dr. Thomas Lavergne; Denis A. Malyshev; Prof. Dr. Floyd E. Romesberg
- Book ID
- 101838189
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 326 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0947-6539
No coin nor oath required. For personal study only.
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The storage and replication of genetic information requires bases that pair stably and selectively in duplex DNA and are also good substrates for DNA polymerases. Though the four natural bases pair by hydrogen bonding, there is no reason to assume that the pairing of two unnatural bases could not be
The storage and replication of genetic information requires bases that pair stably and selectively in duplex DNA and are also good substrates for DNA polymerases. Though the four natural bases pair by hydrogen bonding, there is no reason to assume that the pairing of two unnatural bases could not be