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Polymerase chain reaction (PCR) investigation of chromosome 3 loci in uveal melanoma

✍ Scribed by V. White; K. McNeil; D. Horsman


Book ID
119106014
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
112 KB
Volume
66
Category
Article
ISSN
0165-4608

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Using a polymerase chain reaction/microsatellite marker system, we demonstrated that 6 of 22 (27%) clinical stage B (early) primary prostate tumors showed loss of heterozygosity at one or more of five loci on chromosome 17. The sensitivity of this study was increased by use of a Phosphorlmager and s