Polymer-supported Sulphonic Acid Catalyzed Three-component One-pot Synthesis of α-Amidoalkyl-β-naphthols
✍ Scribed by Li-Tao AN; Xiao-Hua LU; Fei-Qing DING; Wen-Qing JIANG; Jian-Ping ZOU
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 66 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0256-7660
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📜 SIMILAR VOLUMES
## Abstract A simple and efficient method has been developed for the synthesis of __α__‐amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me~3~SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature.
## Abstract magnified image Silica gel supported Phosphomolybdic acid (PMA.SiO~2~) catalyzes efficiently the one‐pot three‐component coupling reaction of anthranilic acid, orthoesters, and amines at room temperature to afford 4(3__H__)‐Quinazolinones in high to excellent yields under solvent‐free c