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Polymer-Supported Ionic Liquid Catalyzed Synthesis of 1,2,3,4-Tetrahydro-2-oxopyrimidine-5-carboxylates via Biginelli Reaction.

✍ Scribed by Zong-Ting Wang; Shu-Chao Wang; Li-Wen Xu


Book ID
101974086
Publisher
John Wiley and Sons
Year
2005
Weight
17 KB
Volume
36
Category
Article
ISSN
0931-7597

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Polymer-Supported Ionic-Liquid-Catalyzed
✍ Zong-Ting Wang; Shu-Chao Wang; Li-Wen Xu πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 German βš– 151 KB

## Abstract The __Biginelli__ reaction between an aromatic aldehyde, ethyl acetoacetate, and urea – catalyzed by polymer‐supported, re‐usable, room‐temperature ionic liquids (RTIL) such as **1b** – was shown to efficiently proceed in glacial AcOH at 100Β° to afford the corresponding pyrimidine‐5‐car