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Polymer effects on the synthetic nucleic acid analogs

โœ Scribed by Inaki, Yoshiaki ;Takemoto, Kiichi

Publisher
Wiley (John Wiley & Sons)
Year
1985
Weight
542 KB
Volume
14
Category
Article
ISSN
0025-116X

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โœฆ Synopsis

Polymer effects on the interaction of nucleic acid bases in oligomer models of synthetic nucleic acid analogs were studied. nucleic acid bases were prepared and ultraviolet spectra and photochemical reactions were studied in order to evaluate the intramolecular and intermolecular interactions between pendant nucleic acid bases in these compounds.

The intramolecular interaction was found to.be caused by the nearest neighboring units, and-bindependent on the remote units.The intramolecular interaction was found to closely relate to the intermolecular interaction of the nucleic acid analogs, and to the photodimerization of thymine bases in the oligomers and in the polymers.

Oligomers of polyethyleneimine derivatives containing

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