Polyinosinic Plus Polycytidylic Acid: A Crystalline Polynucleotide Complex
β Scribed by DAVIES, DAVID R.
- Book ID
- 109607569
- Publisher
- Nature Publishing Group
- Year
- 1960
- Tongue
- English
- Weight
- 237 KB
- Volume
- 186
- Category
- Article
- ISSN
- 0028-0836
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π SIMILAR VOLUMES
Twenty-four patients with cancer and concomitant infections with either herpes virus hominis or varicella zoster virus were treated with polyinosinic-polycytidylic acid (rIn.rCn) to determine: 1) the reliability of rIn.rCn to induce interferon production, and 2) the toxicity of the drug. Seven addit
Titration studies of the 1 : 1 helical polynucleotide complex of polyinosinic acid and polycytidylic acid reveal that these two polymers form a complex when the polycytidylic acid is protonated near p H 3. Sedimentation studies show that the protonated complex also haa a 1 : 1 stoichiometry. However