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Polyhydroxypregnane Glycosides from the Roots of Cynanchum otophyllum

✍ Scribed by Lie-Feng Ma; Wei-Guang Shan; Zha-Jun Zhan

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
192 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Six new polyhydroxypregnane glycosides, namely cynotophyllosides A–F (1–6), together with five known steroids, were isolated from the roots of Cynanchum otophyllum. Their structures were elucidated by extensive spectroscopic methods (especially 2D‐NMR techniques) and acid‐catalyzed hydrolysis. Furthermore, high field 1D‐ and 2D‐NMR experiments were employed to elucidate the structure of 8 previously deduced only on the basis of LC/MS data.

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