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Polygenic control of autoimmune diabetes in nonobese diabetic mice

โœ Scribed by Ghosh, S.; Palmer, S.M.; Rodrigues, N.R.; Cordell, H.J.; Hearne, C.M.; Cornall, R.J.; Prins, J.-B.; McShane, P.; Lathrop, G.M.; Peterson, L.B.

Book ID
109916651
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
666 KB
Volume
4
Category
Article
ISSN
1061-4036

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The in vivo mechanism of regulatory T cell (T(reg) cell) function in controlling autoimmunity remains controversial. Here we have used two-photon laser-scanning microscopy to analyze lymph node priming of diabetogenic T cells and to delineate the mechanisms of T(reg) cell control of autoimmunity in