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Poly(ethylene oxide sulfide): New Poly(ethylene glycol) Derivatives Degradable in Reductive Conditions

✍ Scribed by Lee, Yan; Koo, Heebeom; Jin, Geun-woo; Mo, Heejung; Cho, Min Yi; Park, Jong-Yeun; Choi, Joon Sig; Park, Jong Sang

Book ID
124159763
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
125 KB
Volume
6
Category
Article
ISSN
1525-7797

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## Abstract Reductively degradable multiblock polymers for gene and drug delivery were synthesised by oxidative polycondensation of poly(ethylene glycol)‐cysteine derivatives containing ester or urethane bonds. Hydrolysis of the polymers at pH = 5.5, 7.4 and 8.0 and reductive degradation with gluta