Poly(ethylene glycol)-α-chymotrypsin complex catalytically active in anhydrous isooctane
✍ Scribed by Yoshihiko Murakami; Akira Hirata
- Book ID
- 114399948
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 344 KB
- Volume
- 88
- Category
- Article
- ISSN
- 1389-1723
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📜 SIMILAR VOLUMES
The effectiveness of the covalent modification of a-chymotrypsin with methoxy poly(ethylene glycol) (PEG) to afford its stabilization during encapsulation in poly(lactic-co-glycolic) acid (PLGA) microspheres by a solid-in-oil-in-water method was investigated. a-Chymotrypsin was chemically modified w
a-Chymotrypsin has been modified with poly(ethylene glycols) and proxanols, block-copolymers of poly(propylene oxide) and poly(ethylene oxide). These conjugates were several-fold more thermostable and showed high catalytic activity at elevated concentrations of water-miscible organic cosolvents (alc