Polycyclic pyridazines. II [3]. Synthesis of pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrid-azine derivatives from dimethyl pyrazolo[3,4-d]pyrid-azine-5,6-dicarboxylates as the key intermediates
✍ Scribed by Yoshinori Tominaga; Jiann-Kuan Luo; Lyle W. Castle; Raymond N. Castle
- Book ID
- 112130578
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1993
- Tongue
- English
- Weight
- 443 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0022-152X
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## Abstract magnified image A series of pyrazolo[3,4‐__b__]pyridines has been synthesized by __Friedländer__ condensation of 5‐amino‐pyrazole‐4‐carbaldehyde **1** with active methylene compounds in basic medium. Pyrazolo[4′3′:5,6]pyrido‐[2,3‐__d__]pyrimidines have been synthesized from pyrazolo[3,
## Abstract magnified image The synthetic utility of 1,3‐dipolar cycloaddition of DMAD to sydnones has been exploited in the preparation of new 1‐aryl‐4,5‐dihydro‐1__H__‐pyrazolo[3,4‐__d__]pyridazine‐3,6‐diones **7a‐j** and their aromatic 3,6‐dichloro analogues **8a‐j**. The lactam‐lactim tautomer
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