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Polyclonal chromosomal evolution in a benign mixed salivary gland tumor

✍ Scribed by Joachim Mark; Claes Ekedahl


Book ID
119103577
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
389 KB
Volume
28
Category
Article
ISSN
0165-4608

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The expression of RAS oncogenes in benign and malignant salivary gland tumors was studied by immunohistochemistry and by immunoblotting using monoclonal antibodies recognizing the HRASand KRASgene products. Twenty-eight out of 29 benign pleomorphic adenomas overexpressed p21 whereas only I2 out of I