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Polyamine profiles and growth properties of ornithine decarboxylase overexpressing MCF-7 breast cancer cells in culture

โœ Scribed by Andrea Manni; Rita Wechter; Rhea Grove; Lisa Wei; Julianne Martel; Laurence Demers


Book ID
104873925
Publisher
Springer US
Year
1995
Tongue
English
Weight
728 KB
Volume
34
Category
Article
ISSN
0167-6806

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Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (M