Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (M
✦ LIBER ✦
Overexpression of basic fibroblast growth factor (FGF–2) downregulates Bcl–2 and promotes apoptosis in MCF–7 human breast cancer cells
✍ Scribed by Paul Maloof; Qin Wang; Huisheng Wang; Dana Stein; Thomas N. Denny; Joachim Yahalom; Eyal Fenig; Robert Wieder
- Book ID
- 110233610
- Publisher
- Springer US
- Year
- 1999
- Tongue
- English
- Weight
- 250 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Overexpression of basic fibroblast growt
✍
Robert Wieder; Eyal Fenig; Huisheng Wang; Qin Wang; Shoshana Paglin; Thomas Menz
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 606 KB
Overexpression of basic fibroblast growt
✍
Eyal Fenig; Robert Wieder; Ralph Maxy; Zvi Fuks; Joachim Yahalom
📂
Article
📅
1994
🏛
Elsevier Science
🌐
English
⚖ 143 KB
Specific downregulation of bcl-2 and xIA
✍
Lima, Raquel T; Martins, Luís M; Guimarães, José E; Sambade, Clara; Vasconcelos,
📂
Article
📅
2004
🏛
Nature Publishing Group
🌐
English
⚖ 231 KB
Differential effects of chemotherapeutic
✍
Lai K. Leung; Thomas T.Y. Wang
📂
Article
📅
1999
🏛
Springer US
🌐
English
⚖ 153 KB
Down-regulation of apoptosis-related bcl
✍
Besim Ogretmen; Ahmad R. Safa
📂
Article
📅
1996
🏛
John Wiley and Sons
🌐
French
⚖ 797 KB
Recent studies have shown that high levels of the apoptosisrelated proteins bcl-2 and bcl-x, increase, while over-expression of bcl-x, or bax decreases, resistance to drugs that induce apoptosis in some human cancer cells. In the present report, we investigated whether expression of these apoptosis-
Surfactin Induces Apoptosis and G2/M Arr
✍
Xiaohong Cao; A. H. Wang; R. Z. Jiao; C. L. Wang; D. Z. Mao; L. Yan; B. Zeng
📂
Article
📅
2009
🏛
Springer-Verlag
🌐
English
⚖ 447 KB