Polyamine metabolism and cancer
β Scribed by Thresia Thomas; T. J. Thomas
- Book ID
- 114778034
- Publisher
- Carol Davila University of Medicine Bucharest, Romania
- Year
- 2003
- Tongue
- English
- Weight
- 202 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1582-1838
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π SIMILAR VOLUMES
## Abstract Polyamines are ubiquitous small basic molecules that play multiple essential roles in mammalian physiology. Their cellular content is highly regulated and there is convincing evidence that altered metabolism is involvement in many disease states. Drugs altering polyamine levels may ther
Biosynthesis of the polyamines putrescine, spermidine, and spermine has been found to be activated in tissues with cellular proliferation. In the present study we have investigated polyamine levels and the activity of the first rate-limiting enzyme ornithine decarboxylase (ODC) in tumour samples obt