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Mammalian polyamine metabolism and function

โœ Scribed by Anthony E. Pegg

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
520 KB
Volume
61
Category
Article
ISSN
1521-6543

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โœฆ Synopsis

Abstract

Polyamines are ubiquitous small basic molecules that play multiple essential roles in mammalian physiology. Their cellular content is highly regulated and there is convincing evidence that altered metabolism is involvement in many disease states. Drugs altering polyamine levels may therefore have a variety of important targets. This review will summarize the current state of understanding of polyamine metabolism and function, the regulation of polyamine content, and heritable pathological conditions that may be derived from altered polyamine metabolism. ยฉ 2009 IUBMB IUBMB Life 61(9): 880โ€“894, 2009

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