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Poly(ADP-ribose) polymerase: Molecular biological aspects

✍ Scribed by Gilbert De Murcia; Josiane Ménissier-De Murcia; Valérie Schreiber

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
799 KB
Volume
13
Category
Article
ISSN
0265-9247

No coin nor oath required. For personal study only.

✦ Synopsis

A number of roles have been ascribed to poly(ADPribose) polymerase* including involvement in DNA repair, cell proliferation, differentiation and transformation. Cloning of the gene has allowed the development of molecular biological approaches to elucidate the structure and the function(s) of this highly conserved enzyme. This article will review the recent results obtained in this field.

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