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Poly(ADP-Ribose) in the Cellular Response to DNA Damage

โœ Scribed by Nathan A. Berger


Book ID
121321160
Publisher
Bioone
Year
1985
Tongue
English
Weight
403 KB
Volume
101
Category
Article
ISSN
0033-7587

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โœ Viatcheslav A. Soldatenkov; Mark Smulson ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 301 KB

Poly(ADP-ribose) polymerase (PARP) catalyzes the transfer of successive units of ADP-ribose moiety from NAD ุ‰ covalently to itself and other nuclear acceptor proteins. PARP is a zinc finger-containing protein, allowing the enzyme to bind to either double-or single-strand DNA breaks without any appar