Poly (N-isopropylacrylamide)–PLA and PLA blend nanoparticles for temperature-controllable drug release and intracellular uptake
✍ Scribed by Eri Ayano; Miyuki Karaki; Tsutomu Ishihara; Hideko Kanazawa; Teruo Okano
- Book ID
- 116373966
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 794 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0927-7765
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📜 SIMILAR VOLUMES
## Abstract **Summary:** The model drugs ibuprofen (IBU) and tegafur (T‐Fu) were loaded into poly[__N__‐isopropylacrylamide‐__co__‐(acryloyl __β__‐cyclodextrin)] [P(NIPA‐__co__‐A‐CD)] and PNIPA hydrogels by immersing dried gels in IBU or T‐Fu alcohol solutions until they reached equilibrium. Drug r
## Abstract Temperature‐responsive polymers have become increasingly attractive as carrier for the injectable drug delivery systems. In the present work, we have studied the preparation of poly(__N__‐isopropylacrylamide‐acrylamide‐vinilpyrrolidone) (NIPAAm‐AAm‐VP terpolymer) nanoparticulated terpol