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Polarized Distribution of Glycine Transporter Isoforms in Epithelial and Neuronal Cells

✍ Scribed by Irene Poyatos; Francesca Ruberti; Rodrigo Martı́nez-Maza; Cecilio Giménez; Carlos G. Dotti; Francisco Zafra

Book ID
115637614
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
833 KB
Volume
15
Category
Article
ISSN
1044-7431

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Neuronal dependency of the glycine trans
Neuronal dependency of the glycine transporter GLYT1 expression in glial cells
✍ Francisco Zafra; Irene Poyatos; Cecilio Gimenez 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 364 KB

Two membrane-localized transporter proteins (GLYT1 and GLYT2) are responsible for removal of extracellular glycine in the mammalian CNS. Whereas GLYT1 seems to be expressed mainly in glial cells, GLYT2 is neuronal. The highest concentrations of both transporters are found in glycinergic areas of the