## Abstract For Abstract see ChemInform Abstract in Full Text.
Polar Substitutions in the Benzenesulfonamide Ring of Celecoxib Afford a Potent 1,5-Diarylpyrazole Class of COX-2 Inhibitors.
โ Scribed by Sunil K. Singh; P. Ganapati Reddy; K. Srinivasa Rao; Braj B. Lohray; P. Misra; Shaikh A. Rajjak; Yeleswarapu K. Rao; A. Venkateswarlu
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 99 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
๐ SIMILAR VOLUMES
Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide (SC-58635, Celecoxib). -Claisen condensation, followed by regioselective reaction with the hydrochloride
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